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Psychological stressors involved in the pathogenesis of premature ovarian insufficiency and potential intervention measures

Xu, Ying-Pei Fu, Ji-Chun Hong, Zhi-Lin Zeng, De-Fei Guo, Chao-Qin Li, Ping Wu, Jin-Xiang

Fujian Med Univ Longyan Affiliated Hosp 1 Dept Reprod Med Longyan 361000 Fujian Province Peoples R ChinaFujian Med Univ Sch Basic Med Sci Dept Histol & Embryol Fuzhou 350122 Peoples R ChinaFujian Med Univ Affiliated Hosp 2 Dept Reprod Med Quanzhou Fujian Province Peoples R ChinaFujian Med Univ Affiliated Hosp 2 Clin Lab Ctr Quanzhou Fujian Province Peoples R China

来源 PubMed期刊 ScienceCitationIndex... 详细信息

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关键词： Premature ovarian insufficiency psychological stressors apoptosis telomeres oocyte generation ovarian aging protective therapies NERVE GROWTH-FACTOR LACTOBACILLUS-HELVETICUS R0052 BIFIDOBACTERIUM-LONGUM R0175 UNPREDICTABLE MILD STRESS GRANULOSA-CELL APOPTOSIS OXIDATIVE STRESS HORMONE-I INHIBIN-B DEPRESSION EXPRESSION

HLA-A02 restricted T-cell cross-reactivity to a microbial antigen

Aints, Alar Sunina, Marina Uibo, Raivo

Univ Tartu Inst Biomed & Translat Med Dept Immunol Estonia Ravila 19 EE-50411 Tartu Estonia

来源 ScienceCitationIndex... PubMed期刊详细信息

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关键词： Autoimmunity cross-presentation Type 1 diabetes molecular mimicry immunotoxin IDENTIFICATION

CXCL10 and IL15 co-expressing chimeric antigen receptor T cells enhance anti-tumor effects in gastric cancer by increasing cytotoxic effector cell accumulation and survival

Nie, Siyue Song, Yujie Hu, Kun Zu, Wei Zhang, Fengjiao Chen, Lixia Ma, Qiang Zhou, Zishan Jiao, Shunchang

PLA Med Sch Beijing Peoples R ChinaBeijing DCTY Biotech Co LTD Res & Dev Dept Beijing Peoples R ChinaChinese Peoples Liberat Army Gen Hosp Dept Oncol Med Ctr 5 28 Fuxing Rd Beijing 100853 Peoples R ChinaBeijing DCTY Biotech Co LTD 86 Shuangying West Rd Beijing 102200 Peoples R ChinaCapital Med Univ Dept Funct Neurosurg Beijing Peoples R ChinaCapital Med Univ Dept Funct Neurosurg Xuanwu Hosp Beijing Peoples R China

来源 ScienceCitationIndex... PubMed期刊 T&F期刊详细信息

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关键词： CAR-T cells interleukin 15 CXCL10 infiltration Claudin18.2 CHEMOKINES STEMNESS IMMUNITY GROWTH

Arisaema Cum Bile possesses significantly antiepileptic effects through regulation of PI3K/Akt/Nrf2 signaling pathways

Zhong, Lian He, Chengxun Li, Meiyan Wu, Xu Gou, Yan Geng, Zhao He, Chengjun Zhao, Chongbo Wu, Chunjie

Chengdu Univ Tradit Chinese Med Sch Pharm Chengdu Peoples R ChinaSichuan Testing Ctr Med Devices Sichuan Inst Drug Control Natl Med Prod Adm Key Lab Qual Evaluat Tradit Chin Chengdu Peoples R ChinaChengdu Univ Tradit Chinese Med Sch Pharm 1166Liutai Ave Chengdu 611137 Peoples R ChinaShaanxi Univ Chinese Med Coll Pharm Xianyang Peoples R ChinaShaanxi Univ Chinese Med Coll Pharm Xianyang 712046 Peoples R China

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关键词： Arisaema Cum Bile (ACB) epilepsy network pharmacology PI3K/Akt/Nrf2 signaling pathway apoptosis MITOCHONDRIAL DYSFUNCTION OXIDATIVE STRESS EPILEPSY ANTICONVULSANT PHARMACOLOGY MECHANISMS APOPTOSIS EXTRACT MEMORY GABA

Hyperoxia exposure induces ferroptosis and apoptosis by downregulating PLAGL2 and repressing HIF-1α/VEGF signaling pathway in newborn alveolar typeII epithelial cell

Zhu, Yuting Hou, Hongmei Li, Yawen Zhang, Yanyu Fang, Yuanyuan Chen, Si Zhang, Le Jin, Weilai Zhou, Yahui

Jiangnan Univ Affiliated Childrens Hosp Dept Neonatol Wuxi 214023 Peoples R China

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关键词： Bronchopulmonary dysplasia (BPD) PLAGL 2 HIF-1 alpha/VEGF pathway lung injury BRONCHOPULMONARY DYSPLASIA HYPOXIA LUNG ACTIVATION EXPRESSION PROMOTES MODEL VEGF

Microbiome and pancreatic cancer: time to think about chemotherapy

de Castilhos, Juliana Tillmanns, Katharina Blessing, Jana Larano, Arnelyn Borisov, Vadim Stein-Thoeringer, Christoph K.

Univ Hosp Tuebingen Translat Microbiome Res Internal Med 1 Tubingen GermanyUniv Hosp Tuebingen Res Ctr M3 Tubingen GermanyUniv Tubingen Cluster Excellence Controlling Microbes Fight Infe Tubingen Germany

来源 ScienceCitationIndex... PubMed期刊详细信息

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关键词： Pancreatic Ductal Adenocarcinoma (PDAC) microbiome chemotherapy efficacy microbial metabolism tumor microenvironment INDUCED GASTROINTESTINAL MUCOSITIS HISTONE DEACETYLASE INHIBITOR GUT MICROBIOTA SODIUM-BUTYRATE TUMOR MICROBIOME BREAST-CANCER BETA-GLUCURONIDASE APOPTOSIS IMPACT CELLS

Immunosuppressive treatment results in patients with primary IgA nephropathy in Turkiye; the data from TSN-GOLD working group

Oruc, Aysegul Sumnu, Abdullah Turkmen, Aydin Basturk, Taner Cebeci, Egemen Turgutalp, Kenan Cetinkaya, Hakki Uzerk Kibar, Muege Seyahi, Nurhan Tatar, Erhan Ergul, Metin Derici, Uelver Ayli, Mehmet Deniz Pinar, Musa Bakar, Betuel Kazancioglu, Ruemeyza Yildiz, Abduelmecit Dirim, Ahmet Burak Yilmaz, Zuelfuekar Turkmen, Kueltigin Tunca, Onur Koc, Mehmet Kutlay, Sim Micozkadioglu, Hasan Azak, Alper Boztepe, Burcu Ustundag, Sedat Safak Ozturk, Seda Unsal, Abdulkadir Karadag, Serhat Sahin, Guelizar Yenigun, Ezgi Cosgun Eren, Necmi Gullulu, Mustafa Gursu, Meltem Ozturk, Savas

Bursa Uludag Univ Fac Med Dept Nephrol TR-16059 Bursa TurkiyeMedipol Univ Fac Med Dept Nephrol Istanbul TurkiyeIstanbul Univ Fac Med Dept Nephrol Istanbul TurkiyeUniv Hlth Sci Etfal Hamidiye Training & Res Hosp Dept Nephrol Istanbul TurkiyeIstanbul Haseki Training & Res Hosp Istanbul Prov Directorate Hlth Dept Nephrol Istanbul TurkiyeMersin Univ Training & Educ Hosp Fac Med Dept Nephrol Mersin TurkiyeUniv Hlth Sci Sultan 2 Abdulhamid Han Training & Res Hosp Dept Nephrol Istanbul TurkiyeAnkara Bilkent City Hosp Hlth Minist Turkiye Republ Dept Nephrol Ankara TurkiyeIstanbul Univ Cerrahpasa Fac Med Dept Nephrol Istanbul TurkiyeBozyaka Educ & Res Hosp Izmir Prov Directorate Hlth Dept Nephrol Izmir TurkiyeKocaeli Univ Fac Med Dept Nephrol Kocaeli TurkiyeGazi Univ Fac Med Dept Nephrol Ankara TurkiyeDiskapi Yildirim Beyazit Training & Res Hosp Minist Hlth Dept Nephrol Ankara TurkiyeSakarya Univ Fac Med Dept Nephrol Sakarya TurkiyeAnkara Numune Training & Res Hosp Ankara Prov Hlth Directorate Dept Nephrol Ankara TurkiyeBezmialem Vakif Univ Fac Med Dept Nephrol Istanbul TurkiyeIstanbul Bakirkoy Dr Sadi Konuk Educ & Res Hosp Istanbul Prov Hlth Directorate Dept Nephrol Istanbul TurkiyeDicle Univ Fac Med Dept Nephrol Diyarbakir TurkiyeNecmettin Erbakan Univ Meram Fac Med Hosp Dept Nephrol Konya TurkiyeAfyonkarahisar Univ Hlth Sci Fac Med Dept Nephrol Afyonkarahisar TurkiyeMarmara Univ Fac Med Dept Nephrol Istanbul TurkiyeAnkara Univ Fac Med Dept Nephrol Ankara TurkiyeBaskent Univ Dr Turgut Noyan Adana Applicat & Res Hosp Fac Med Dept Nephrol Adana TurkiyeAtaturk City Hosp Balikesir Prov Hlth Directorate Dept Nephrol Balikesir TurkiyeHaydarpasa Numune Training & Res Hosp Istanbul Prov Hlth Directorate Dept Nephrol Istanbul TurkiyeTrakya Univ Fac Med Dept Nephrol Edirne Turkiye

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关键词： IgA nephropathy immunosuppressive treatment Turkiye remission outcome ORAL METHYLPREDNISOLONE SUPPORTIVE CARE PATHOGENESIS PREDNISONE OUTCOMES THERAPY

Hyperbaric oxygen augments susceptibility to C. difficile infection by impairing gut microbiota ability to stimulate the HIF-1α-IL-22 axis in ILC3

Fachi, Jose L. Pral, Lais. P. Assis, Helder C. Oliveira, Sarah Rodovalho, Vinicius R. dos Santos, Jefferson A. C. Fernandes, Mariane F. Matheus, Valquiria A. Sesti-Costa, Renata Basso, Paulo J. Floro e Silva, Marina Camara, Niels O. S. Giorgio, Selma Colonna, Marco Vinolo, Marco A. R.

Washington Univ Sch Med Dept Pathol & Immunol St Louis MO USAWashington Univ Sch Med Dept Pathol & Immunol 660 S Euclid Ave St Louis MO 63110 USAUniv Estadual Campinas Inst Biol Dept Genet & Evolut Microbiol & Immunol Campinas BrazilUniv Estadual Campinas Inst Biol Expt Med Res Cluster Campinas BrazilUniv Estadual Campinas Obes & Comorbid Res Ctr OCRC Brazi RomaniaUniv Estadual Campinas Inst Biol Dept Genet & Evolut Microbiol & Immunol 255 Monteiro Lobato St BR-13083862 Campinas SP BrazilUniv Estadual Campinas Hematol & Hemotherapy Ctr Campinas BrazilUniv Sao Paulo Inst Biomed Sci Dept Immunol Sao Paulo BrazilUniv Estadual Campinas Inst Biol Dept Anim Biol Campinas Brazil

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关键词： Hyperbaric oxygen microbiota butyrate clostridioides difficile innate lymphoid cells ILC3 HIF-1 CHAIN FATTY-ACIDS CLOSTRIDIUM-DIFFICILE AKKERMANSIA-MUCINIPHILA INTESTINAL MICROBIOTA COLONIZATION RESISTANCE MOUSE MODEL T-BET HYPOXIA ACTIVATION THERAPY

New imidazole-2-thiones linked to acenaphythylenone as dual DNA intercalators and topoisomerase II inhibitors: structural optimization, docking, and apoptosis studies

Mohamed, Asmaa H. Alshammari, Mohammed B. Aly, Ashraf A. Sadek, Kamal U. Ahmad, Akil Aziz, Eman A. El-Yazbi, Amira F. El-Agroudy, Eman J. Abdelaziz, Marwa E.

Minia Univ Fac Sci Chem Dept El Minia EgyptMinia Univ Fac Sci Chem Dept El Minia 61519 EgyptPrince Sattam Bin Abdulaziz Univ Coll Sci & Humanities Chem Dept Al Kharij Saudi ArabiaAlexandria Univ Fac Pharm Dept Pharmaceut Analyt Chem Alexandria EgyptAlexandria Univ Fac Pharm Dept Pharmaceut Chem Alexandria Egypt

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关键词： New imidazole-2-thiones DNA intercalators topoisomerase II inhibitor doxorubicin dual anticancer activity BIOLOGICAL EVALUATION DERIVATIVES DESIGN COMPLEXES IMIDAZOLE TOXICITY AGENTS TRANSPORTERS ABSORPTION ENZYMES

Mesenchymal stem cell-derived exosomes ameliorate diabetic kidney disease through NOD2 signaling pathway

Wang, Yinghui Lu, Donglin Lv, Shasha Liu, Xiangchun Liu, Gang

Shandong Univ Hosp 2 Multidisciplinary Innovat Ctr Nephrol Dept NephrolCheeloo Coll Med Jinan Shandong Peoples R ChinaShandong Univ Nephrol Res Inst Jinan Shandong Peoples R ChinaShandong Univ Key Lab Reprod Endocrinol Minist Educ Jinan Shandong Peoples R China

来源 ScienceCitationIndex... T&F期刊 PubMed期刊详细信息

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关键词： Diabetic kidney disease exosomes mesenchymal stem cells NOD2 TOLL-LIKE RECEPTORS NEPHROPATHY TRANSPLANTATION ACTIVATION MECHANISMS PREVENTION

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